This edition of the Burden of Musculoskeletal Diseases in the United States continues to use condition codes defined in ICD-9-CM based on 2014 data. The earliest data based on ICD-10-CM codes will be 2016, with a one to two-year lag in availability. Codes used in the economic impact analysis by musculoskeletal diseases fall into the two categories of base codes and expansive codes.
Conditions included in the base musculoskeletal disease rubric include spine conditions, arthritis and joint pain, the category that includes osteoporosis (other diseases of bone and cartilage), injuries, and an inclusive “other” category for the remaining conditions. Conditions selected for the cost analysis presented are based on condition topics included in this site. Data are reported primarily for base case ICD-9-CM codes, or those codes for which musculoskeletal disease is the principal cause of the condition rather than a consequence of another major health condition (e.g., bone cancer metastases from an other primary cancer site).
Estimates are also provided for a more expansive list of codes of musculoskeletal-related diseases that include conditions for which musculoskeletal diseases are either the primary and secondary cause of the condition. This more expansive list of conditions yields a vastly larger prevalence estimate than the base case list. However, it is reasonable to assume the cost of musculoskeletal diseases probably exceeds the conservative estimates presented here. For example, a person with bone metastases would incur costs to treat the bone manifestation, even though the cancer, not the bone condition, is the primary etiology.
ICD-9-CM codes included in each subcategory for the base and expansive conditions are listed in subsections.
Spine
Special Symptoms or Syndromes, NEC : 307
Migraine : 346
Trigeminal Nerve Disorders : 350
Nerve Root and Plexus Disorders : 353
Dentofacial Anomalies, Including Malocclusion : 524
Pain and Other Symptoms Associated with Female Genital organs : 625
Menopausal and Postmenopausal Disorders : 627
General Symptoms : 780
Symptoms Involving Skin and Other Integumentary Tissue : 782
Symptoms Involving Head and Neck : 784
Symptoms Involving Respiratory System and Other Chest Symptoms : 786
Symptoms Involving Digestive System : 787
Other Symptoms Involving Abdomen and Pelvis : 789
Injury to Other Cranial Nerve(s) : 951
Injury to Nerve Roots and Spinal Plexus : 953
Arthritis and Joint Pain
Gonococcal Infections : 098
Other Venereal Diseases : 099
Other and Unspecified Infectious and Parasitic Diseases : 136
Other and Unspecified Disorders of Metabolism : 277
Purpura and Other Hemorrhagic Conditions : 287
Other Paralytic Syndromes : 344
Mononeuritis of Upper Limb and Mononeuritis Multiplex : 354
Inflammatory and Toxic Neuropathy : 357
Other and Ill-defined Cerebrovascular Disease : 437
Other Peripheral Vascular Disease : 443
Polyarteritis Nodosa and Allied Conditions : 446
Other Disorders of Arteries and Arterioles : 447
Psoriasis and Similar Disorders : 696
Osteoporosis
Other Disorders of Bone and Cartilage : 733
Musculoskeletal Injuries
Open Wound of Neck : 874
Open Wound of Other and Unspecified Sites, Except Limbs : 879
Contusion of Trunk : 922
Contusion of Upper Limb : 923
Contusion of Lower Limb and of Other and Unspecified Sites : 924
Crushing Injury of Trunk : 926
Other Musculoskeletal Conditions
Other Salmonella Infections : 3
Rat-bite Fever : 26
Meningococcal Infection : 36
Rubella : 56
Other Arthropod-borne Diseases : 88
Early Syphilis, Symptomatic : 91
Other forms of Late Syphilis, with Symptoms : 95
Yaws : 102
Late Effects of Tuberculosis : 137
Malignant Neoplasm of Other and Ill-defined Sites : 195
Secondary Malignant Neoplasm of Other Specified Sites : 198
Other Malignant Neoplasms of Lymphoid and Histiocytic Tissue : 202
Multiple Myeloma and Immunoproliferative Neoplasms : 203
Other Benign Neoplasm of Connective and Other Soft Tissue : 215
Neoplasm of Uncertain Behavior of Other and Unspecified Sites and Tissues : 238
Neoplasms of Unspecified Nature : 239
Disorders of Parathyroid Gland : 252
Disorders of Lipoid Metabolism : 272
Disorders of Mineral Metabolism : 275
Hereditary Hemolytic Anemias : 282
Organic Sleep Disorders : 327
Mononeuritis of Lower Limb and Unspecified Site : 355
Peritonitis and Retroperitoneal Infections : 567
Other Cellulitis and Abscess : 682
Other and Unspecified Congenital Anomalies : 759
Late Effects of Injuries to Skin and Subcutaneous Tissues : 906
Certain Early Complications of Trauma : 958
Complications Peculiar to Certain Specified Procedures : 996
Personal History of Other Diseases : V13
Organ or Tissue Replaced By Transplant : V42
Organ or Tissue Replaced By Other Means : V43
Other Postprocedural States : V45
Problems with Head, Neck, and Trunk : V48
Fitting and Adjustment of Other Device : V53
Convalescence and Palliative Care : V66
Follow-up Examination : V67
Special Screening Examination for Bacterial and Spirochetal Diseases : V74
Spine
Special Symptoms or Syndromes, NEC : 307
Migraine : 346
Trigeminal Nerve Disorders : 350
Nerve Root and Plexus Disorders : 353
Dentofacial Anomalies, Including Malocclusion : 524
Pain and Other Symptoms Associated with Female Genital Organs : 625
Menopausal and Postmenopausal Disorders : 627
General Symptoms : 780
Symptoms Involving Skin and Other Integumentary Tissue : 782
Symptoms Involving Head and Neck : 784
Symptoms Involving Respiratory System and Other Chest Symptoms : 786
Symptoms Involving Digestive System : 787
Other Symptoms Involving Abdomen and Pelvis : 789
Injury to Other Cranial Nerve(s) : 951
Injury to Nerve Roots and Spinal Plexus : 953
Arthritis and Joint Pain
Gonococcal Infections : 098
Other Venereal Diseases : 099
Other and Unspecified Infectious and Parasitic Diseases : 136
Other and Unspecified Disorders of Metabolism : 277
Purpura and Other Hemorrhagic Conditions : 287
Other Paralytic Syndromes : 344
Mononeuritis of Upper Limb and Mononeuritis Multiplex : 354
Inflammatory and Toxic Neuropathy : 357
Other and Ill-defined Cerebrovascular Disease : 437
Other Peripheral Vascular Disease : 443
Polyarteritis Nodosa and Allied Conditions : 446
Other Disorders of Arteries and Arterioles : 447
Psoriasis and Similar Disorders : 696
Osteoporosis
Due to small sample sizes, no additional codes were included in the expansive analysis
Musculoskeletal Injuries
Open Wound of Neck : 874
Open Wound of Other and Unspecified Sites, Except Limbs : 879
Contusion of Trunk : 922
Contusion of Upper Limb : 923
Contusion of Lower Limb and of Other and Unspecified Sites : 924
Crushing Injury of Trunk : 926
Other Musculoskeletal Conditions
Other Salmonella Infections : 3
Rat-bite Fever : 26
Meningococcal Infection : 36
Rubella : 56
Other Arthropod-borne Diseases : 88
Early Syphilis, Symptomatic : 91
Other forms of Late Syphilis, with Symptoms : 95
Yaws : 102
Late Effects of Tuberculosis : 137
Malignant Neoplasm of Other and Ill-defined Sites : 195
Secondary Malignant Neoplasm of Other Specified Sites : 198
Other Malignant Neoplasms of Lymphoid and Histiocytic Tissue : 202
Multiple Myeloma and Immunoproliferative Neoplasms : 203
Other Benign Neoplasm of Connective and Other Soft Tissue : 215
Neoplasm of Uncertain Behavior of Other and Unspecified Sites and Tissues : 238
Neoplasms of Unspecified Nature : 239
Disorders of Parathyroid Gland : 252
Disorders of Lipoid Metabolism : 272
Disorders of Mineral Metabolism : 275
Hereditary Hemolytic Anemias : 282
Organic Sleep Disorders : 327
Mononeuritis of Lower Limb and Unspecified Site : 355
Peritonitis and Retroperitoneal Infections : 567
Other Cellulitis and Abscess : 682
Other and Unspecified Congenital Anomalies : 759
Late Effects of Injuries to Skin and Subcutaneous Tissues : 906
Certain Early Complications of Trauma : 958
Complications Peculiar to Certain Specified Procedures : 996
Personal History of Other Diseases : V13
Organ or Tissue Replaced By Transplant : V42
Organ or Tissue Replaced By Other Means : V43
Other Postprocedural States : V45
Problems with Head, Neck, and Trunk : V48
Fitting and Adjustment of Other Device : V53
Convalescence and Palliative Care : V66
Follow-up Examination : V67
Special Screening Examination for Bacterial and Spirochetal Diseases : V74
Arthritis and Spine Conditions
Gout : 274
Osteoarthritis and Allied Diseases : 714, priority nonRA with self-report of 716 or 719
Rheumatoid Arthritis : 714 and priority RA
Other/Unspecified Disorders of the Back : 724
Connective Tissue Disease : 710.9